A systematic review of 107 alcohol studies that accounted for potential confounding from former drinker bias and other study-level covariates found no significant protective associations of occasional or low-volume drinking (moderate drinking) with all-cause mortality.1
There was an increased risk of all-cause mortality for drinkers who drank over 25 gms/day (1 can of beer = 14 gms, 150 ml of wine = 14 gms) and a significantly increased risk when drinking 45 gms or more per day.
There was a significantly increased risk of all-cause mortality among female drinkers who drank 25 or more gms per day, and male drinkers who drank 45 or more gms per day.
As published in NZ Doctor and Research Review